Xilai Gao African Swine Fever Prevention (Part 3)

Release time: 2019-03-01

【Summary Description】 Xilai Gao’s African Swine Fever Prevention (Part 3): Toxin Management for Protecting Susceptible Animals As the old saying goes, as long as your body is strong, you can resist any disease. The health condition of susceptible animals determines the strength of their nonspecific immune defenses. Everyone is probably familiar with the saying, “Toxins are the root of all diseases.” However, to truly address the issue of toxins—especially mycotoxins—we need to take a fresh look at mycotoxins themselves and the agents used to manage them. First, let’s examine the toxins themselves; then, let’s take a closer look: This survey report reveals that mycotoxin contamination is extremely severe. Now, let’s continue and explore how each type of mycotoxin harms the body.

Xilai Gao African Swine Fever Prevention (Part 3)

Toxin Treatment for Protecting Susceptible Animals

As the saying goes, as long as your body is strong, you can resist any illness. The health condition of susceptible animals determines the strength of their nonspecific immunity.

“The phrase ‘Toxins are the root of all diseases’ should be familiar to everyone. However, to truly address toxins—especially mycotoxins—we need to take a fresh look at mycotoxins themselves and the agents used to manage them.”

First, let's look at the toxin:

Take another look:

This survey report indicates that mycotoxin contamination is extremely severe.

Keep reading.

So, what are the specific harmful effects of each mycotoxin on the body?

Aflatoxin:

Aflatoxin poisoning (Aflatoxicosis) primarily damages the livers of animals, and the severity of the damage varies depending on the animal species, age, sex, and nutritional status. Research findings indicate that aflatoxins can lead to impaired liver function, reduced milk production, and... Laying hen Egg-laying rate and weaken the animal's immunity , Low susceptibility to infection by harmful microorganisms 。 In addition, long-term consumption of foods containing low concentrations of aflatoxins... Feed It can also cause embryonic poisoning. Young animals are typically more sensitive to aflatoxins. The clinical manifestations of aflatoxin poisoning include disturbances in the digestive system. 、 Reduced fertility 、 Reducing feed utilization rate 、 Anemia, etc. 。 Aflatoxins not only reduce milk yield in dairy cows but also cause the milk to contain transformed aflatoxins. M1 and M2. According to statistics from U.S. agricultural economists, feeding animals with feed contaminated by aflatoxins results in at least—each year— U.S. livestock industry To suffer 10% economic loss. In China, the resulting losses in animal husbandry could be even greater. Aflatoxins can cause atrophy of the bursa of Fabricius and thymus in poultry, subcutaneous hemorrhaging, poor responsiveness, reduced immunity, vaccine failure, increased susceptibility to infectious diseases, smaller eggs, lower yolk weight, decreased fertilization and hatchability rates, increased embryonic mortality, and the production of unhealthy chicks. In livestock, aflatoxins lead to slow growth, reduced feed conversion efficiency, jaundice, rough coat and skin, hypoproteinemia, liver cancer, and immunosuppression. 。

Zearalenone ( F2 toxin) :

Zearalenone has estrogenic effects and primarily targets the reproductive system, causing hyperestrogenism in livestock, poultry, and laboratory mice. In pregnant animals, ( Including people ) Consuming foods containing zearalenone can cause miscarriage, stillbirth, and birth defects. Eating various flour-based foods made from wheat infected with fusarium head blight can also lead to poisoning symptoms affecting the central nervous system, such as nausea, chills, headache, depression, and ataxia.

  Vomitoxin ( T-2 Toxin)

T-2 The toxins primarily affect the blood, liver, kidneys, pancreatic muscles, and... Lymphocyte the function of, T-2 Toxin The typical clinical symptoms following poisoning include anorexia, vomiting, diarrhea, growth stagnation, reproductive disorders, and neurological dysfunction.

Ochratoxin A

Amino acid blockade tRNA The action of synthetase affects protein synthesis, causing... IgA 、 IgG and IgM Reduce, antibody titer decreases.

It damages the bursa of Fabricius in birds and the lymphoid tissues in the intestines of livestock and poultry, reducing antibody production and impairing humoral immunity.

It leads to a decrease in the phagocytic capacity of granulocytes, thereby impairing phagocytosis and cellular immunity.

Ochratoxin A The ability to affect the development and maturation of fetal tissues and organs via the placenta is associated with the carcinogenic effects of ochratoxin.

Ochratoxin primarily damages the liver and kidneys of animals. This toxin mainly causes kidney injury, and large amounts of the toxin can also induce inflammation and necrosis of the intestinal mucosa in animals. Its teratogenic effects have also been observed in animal experiments.

Aflatoxin:

Aflatoxin poisoning in pigs leads to impaired production and reproductive performance, with the following prominent symptoms: Pulmonary edema Embryonic development is impaired, and immune function is reduced.

The symptoms of poisoning are summarized as follows:

Reduced production and reproductive performance; embryonic mortality; acute respiratory distress; pulmonary edema; cyanosis (bluish discoloration of the skin); jaundice; impaired immune function

In summary, simply put, mycotoxins can damage the liver, kidneys, digestive tract, lungs, and other organs, leading to reduced immunity and impaired production performance.

Also, please take a look.

A large body of research indicates that mycotoxin adsorbents exhibit the following adsorption characteristics for toxins:

Therefore, the adsorption method can effectively address aflatoxins and ergot alkaloids. However, for ochratoxin A, fumonisin, and zearalenone... T2 toxin and vomitoxin are powerless.

What to do:

     

Netherlands Xilai Gao and Hungary In cooperation with Libada Company.

Here’s a simple explanation about Bada Company:

The launch of Bada Company’s second-generation mycotoxin detoxification and degradation enzyme finally marks the birth of a true mycotoxin treatment agent—the enhanced Anbaiqing from Dutch Kemin.

 

Attention, 1. The pH value in the pig’s stomach ranges between 3.0 and 5.0. As shown in the line graph above, the enhanced mycotoxin detoxification and degradation enzyme complex exhibits a toxin removal efficiency of 95% to 100% in the stomach.

After the pigs eat the feed, it travels from the stomach to the duodenum before being excreted. It takes... 3-5 hours.

 

Adsorption

Biological Transformation of Zearalenone

 

T2 Biotransformation of Toxins

Biodegradation of Ochratoxin A

Aflatoxin inactivation

Enhanced Dosage and Administration of Anbaiqing

 

Enhanced Anbaiqing

World-class, uniquely domestic—comprehensive adsorption enzymatic hydrolysis.

To prevent and control African swine fever, addressing toxins should naturally be the top priority.